PT - JOURNAL ARTICLE AU - William F. Martin AU - Mayo Roettger AU - Chuan Ku AU - Sriram G. Garg AU - Shijulal Nelson-Sathi AU - Giddy Landan TI - Late mitochondrial origin is pure artefact AID - 10.1101/055368 DP - 2016 Jan 01 TA - bioRxiv PG - 055368 4099 - http://biorxiv.org/content/early/2016/05/25/055368.short 4100 - http://biorxiv.org/content/early/2016/05/25/055368.full AB - Pittis and Gabaldón1 recently claimed that the mitochondrion came late in eukaryotic evolution, following an earlier phase of evolution in which the eukaryotic host lineage acquired genes from bacteria. Here we show that their paper has multiple fatal flaws founded in inappropriate statistical methods and analyses, in addition to erroneous interpretations.