TY - JOUR T1 - Chronically implantable LED arrays for behavioral optogenetics in primates JF - bioRxiv DO - 10.1101/2020.09.10.291583 SP - 2020.09.10.291583 AU - Rishi Rajalingham AU - Michael Sorenson AU - Reza Azadi AU - Simon Bohn AU - James J DiCarlo AU - Arash Afraz Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/09/11/2020.09.10.291583.abstract N2 - Challenges in behavioral optogenetics in large brains demand development of a chronically implantable platform for light delivery. We have developed Opto-Array, a chronically implantable array of LEDs for high-throughput optogenetic perturbation in non-human primates. We tested the Opto-Array in the primary visual cortex of a macaque monkey, and demonstrated that optogenetic cortical silencing by the Opto-Array results in reliable retinotopic visual deficits on a luminance discrimination task.Competing Interest StatementM.S. is a principal engineer at Blackrock Microsystems (Utah). ER -