RT Journal Article
SR Electronic
T1 Distinct place cell dynamics in CA1 and CA3 encode experience in new contexts
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.09.10.292177
DO 10.1101/2020.09.10.292177
A1 Can Dong
A1 Mark E. J. Sheffield
YR 2020
UL http://biorxiv.org/content/early/2020/09/11/2020.09.10.292177.abstract
AB We compared trial-by-trial dynamics of place cells in CA1 and CA3 in new contexts across days. We found that CA1 place fields form early but shift backwards with experience and partially remap across days. In contrast, CA3 place fields develop gradually but remain stable with experience and across days. This suggests distinct plasticity mechanisms drive the formation and dynamics of place fields in CA1 and CA3 to encode distinct features of experience.Competing Interest StatementThe authors have declared no competing interest.