RT Journal Article SR Electronic T1 Comparative Population Genomics of Bread Wheat (Triticum aestivum) Reveals Its Cultivation and Breeding History in China JF bioRxiv FD Cold Spring Harbor Laboratory SP 519587 DO 10.1101/519587 A1 Haofeng Chen A1 Chengzhi Jiao A1 Ying Wang A1 Yuange Wang A1 Caihuan Tian A1 Haopeng Yu A1 Jing Wang A1 Xiangfeng Wang A1 Fei Lu A1 Xiangdong Fu A1 Yongbiao Xue A1 Wenkai Jiang A1 Hongqing Ling A1 Hongfeng Lu A1 Yuling Jiao YR 2019 UL http://biorxiv.org/content/early/2019/01/14/519587.abstract AB The evolution of bread wheat (Triticum aestivum) is distinctive in that domestication, natural hybridization, and allopolyploid speciation have all had significant effects on the diversification of its genome. Wheat was spread around the world by humans and has been cultivated in China for ~4,600 years. Here, we report a comprehensive assessment of the evolution of wheat based on the genome-wide resequencing of 120 representative landraces and elite wheat accessions from China and other representative regions. We found substantially higher genetic diversity in the A and B subgenomes than in the D subgenome. Notably, the A and B subgenomes of the modern Chinese elite cultivars were mainly derived from European landraces, while Chinese landraces had a greater contribution to their D subgenomes. The duplicated copies of homoeologous genes from the A, B, and D subgenomes were commonly found to be under different levels of selection. Our genome-wide assessment of the genetic changes associated with wheat breeding in China provides new strategies and practical targets for future breeding.