RT Journal Article
SR Electronic
T1 Higher-order thalamic implication in the processing of bilateral sensory events
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.05.01.073098
DO 10.1101/2020.05.01.073098
A1 Castejon, Carlos
A1 Nuñez, Angel
YR 2020
UL http://biorxiv.org/content/early/2020/09/29/2020.05.01.073098.abstract
AB In the rodent whisker system, it is well assumed that VPM and POm encode stimulations of the contralateral whisker pad. However, during tactile exploration whiskers are usually stimulated bilaterally. Accordingly, the integration of tactile information from the two sides of the body seems to be fundamental in the processing of these events. Here, to investigate whether POm could be able to codify these bilateral dynamics, whisker-evoked responses in this thalamic nucleus were examined by in vivo extracellular recordings in anesthetized rats using contralateral and ipsilateral stimuli. Strikingly, we found that POm is also able to respond to tactile stimulation of ipsilateral whiskers. Our findings reveal the implication of POm in the representation of bilateral tactile events by integrating simultaneous signals arising from both whisker pads and demonstrate the implication of the higher-order sensory thalamus in the encoding of bilateral sensory events. This can have important implications in bilateral perceptual function.Competing Interest StatementThe authors have declared no competing interest.