TY - JOUR T1 - Expanding the Galaxy’s reference data JF - bioRxiv DO - 10.1101/2020.10.09.327114 SP - 2020.10.09.327114 AU - Nagampalli VijayKrishna AU - Jayadev Joshi AU - Nate Coraor AU - Jennifer Hillman-Jackson AU - Dave Bouvier AU - Marius van den Beek AU - Ignacio Eguinoa AU - Frederik Coppens AU - Sergey Golitsynskiy AU - Michał Stolarczyk AU - Nathan C. Sheffield AU - Simon Gladman AU - Gianmauro Cuccuru AU - Björn Grüning AU - Nicola Soranzo AU - Helena Rasche AU - Bradley W. Langhorst AU - Matthias Bernt AU - Dan Fornika AU - David Anderson de Lima Morais AU - Michel Barrette AU - Peter van Heusden AU - Mauro Petrillo AU - Antonio Puertas-Gallardo AU - Alex Patak AU - Hans-Rudolf Hotz AU - Daniel Blankenberg Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/10/10/2020.10.09.327114.abstract N2 - Summary Properly and effectively managing reference datasets is an important task for many bioinformatics analyses. Refgenie is a reference asset management system that allows to easily organize, retrieve, and share such datasets. Here, we describe the integration of refgenie into the Galaxy platform. Server administrators are able to configure Galaxy to make use of reference datasets made available on a refgenie instance. Additionally, a Galaxy Data Manager tool has been developed to provide a graphical interface to refgenie’s remote reference retrieval functionality. A large collection of reference datasets has also been made available using the CVMFS repository from GalaxyProject.org, with mirrors across the United States, Canada, Europe, and Australia, enabling easy use outside of Galaxy.Availability and implementation The ability of Galaxy to use refgenie assets was added to the core Galaxy framework in version 20.05, which is available from https://github.com/galaxyproject/galaxy under the Academic Free License version 3.0. The refgenie Data Manager tool can be installed via the Galaxy ToolShed, with source code managed at https://github.com/galaxyproject/tools-iuc/data_managers/data_manager_refgenie_pull and released using an MIT license.Competing Interest StatementDaniel Blankenberg and Nate Coraor have a significant financial interest in GalaxyWorks, a company that may have a commercial interest in the results of this research and technology. This potential conflict of interest has been reviewed and is managed by their respective institutions. ER -