RT Journal Article
SR Electronic
T1 Spatial modulation of visual signals arises in cortex with active navigation
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 832915
DO 10.1101/832915
A1 E. Mika Diamanti
A1 Charu Bai Reddy
A1 Sylvia Schröder
A1 Tomaso Muzzu
A1 Kenneth D. Harris
A1 Aman B. Saleem
A1 Matteo Carandini
YR 2020
UL http://biorxiv.org/content/early/2020/10/10/832915.abstract
AB During navigation, the visual responses of neurons in primary visual cortex (V1) are modulated by the animal’s spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but largely absent in the main thalamic pathway into V1. Similar to hippocampus, spatial modulation in visual cortex strengthens with experience and requires engagement in active behavior. Active navigation in a familiar environment, therefore, determines spatial modulation of visual signals starting in the cortex.Competing Interest StatementThe authors have declared no competing interest.