RT Journal Article SR Electronic T1 Practice modifies the response to errors during a novel motor sequence learning task JF bioRxiv FD Cold Spring Harbor Laboratory SP 2020.10.09.334169 DO 10.1101/2020.10.09.334169 A1 Dhanush Rachaveti A1 Rajiv Ranganathan A1 Varadhan SKM YR 2020 UL http://biorxiv.org/content/early/2020/10/10/2020.10.09.334169.abstract AB The occurrence of an error when performing a motor sequence causes an immediate reduction in speed on subsequent trials, which is referred to as post-error slowing. However, understanding how post-error slowing changes with practice has been difficult because it requires extended practice on a novel sequence task. To address this issue, we examined post-error slowing in a novel glove-based typing task that participants performed for 15 consecutive days. Speed and accuracy improved from the early to middle stages of practice, but did not show any further improvements between middle and late stage of practice. However, when we analyzed the response to errors, we found that participants decreased both the magnitude and duration of post-error slowing with practice, even after there were no detectable improvements in overall task performance. These results indicate that learning not only improves overall task performance but also modifies the ability to respond to errors.Competing Interest StatementThe authors have declared no competing interest.