RT Journal Article
SR Electronic
T1 OmicLoupe: Facilitating biological discovery by interactive exploration of multiple omic datasets and statistical comparisons
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.10.22.349944
DO 10.1101/2020.10.22.349944
A1 Jakob Willforss
A1 Valentina Siino
A1 Fredrik Levander
YR 2020
UL http://biorxiv.org/content/early/2020/10/22/2020.10.22.349944.abstract
AB Visual exploration of gene product behavior across multiple omic datasets can pinpoint technical limitations in data and reveal biological trends. The OmicLoupe software was developed to facilitate such exploration and provides more than 15 interactive cross-dataset visualizations for omic data. It expands visualizations to multiple datasets for quality control, statistical comparisons and overlap and correlation analyses, while allowing for rapid inspection and downloading of selected features. The usage of OmicLoupe is demonstrated in three diverse studies, including an analysis of SARS-CoV-2 infection across omic layers, based on previously published proteomics and transcriptomics studies. OmicLoupe is available at quantitativeproteomics.org/omicloupeCompeting Interest StatementThe authors have declared no competing interest.