TY - JOUR T1 - Kilohertz in vivo imaging of neural activity JF - bioRxiv DO - 10.1101/543058 SP - 543058 AU - Jianglai Wu AU - Yajie liang AU - Ching-Lung Hsu AU - Mariya Chavarha AU - Stephen Evans AU - Dongqing Shi AU - Michael Lin AU - Kevin Tsia AU - Na Ji Y1 - 2019/01/01 UR - http://biorxiv.org/content/early/2019/02/06/543058.abstract N2 - Understanding information processing in the brain requires us to monitor neural activity in vivo at high spatiotemporal resolution. Using an ultrafast two-photon fluorescence microscope (2PFM) empowered by all-optical laser scanning, we imaged neural activity in vivo at 1,000 frames per second and submicron spatial resolution. This ultrafast imaging method enabled monitoring of electrical activity down to 300 μm below the brain surface in head fixed awake mice. ER -