RT Journal Article
SR Electronic
T1 Stimulus-specific plasticity of macaque V1 spike rates and gamma
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.11.13.381418
DO 10.1101/2020.11.13.381418
A1 Alina Peter
A1 Benjamin J. Stauch
A1 Katharine Shapcott
A1 Kleopatra Kouroupaki
A1 Joscha T. Schmiedt
A1 Liane Klein
A1 Johanna Klon-Lipok
A1 Jarrod R. Dowdall
A1 Marieke L. Schölvinck
A1 Martin Vinck
A1 Wolf Singer
A1 Michael C. Schmid
A1 Pascal Fries
YR 2020
UL http://biorxiv.org/content/early/2020/11/15/2020.11.13.381418.abstract
AB When a visual stimulus is repeated, average neuronal responses typically decrease, yet they might maintain or even increase their impact through increased synchronization. Previous work has found that many repetitions of a grating lead to increasing gamma-band synchronization. Here we show in awake macaque area V1 that both, repetition-related reductions in firing rate and increases in gamma are specific to the repeated stimulus. These effects showed some persistence on the timescale of minutes. Further, gamma increases were specific to the presented stimulus location. Importantly, repetition effects on gamma and on firing rates generalized to natural images. These findings suggest that gamma-band synchronization subserves the adaptive processing of repeated stimulus encounters, both for generating efficient stimulus responses and possibly for memory formation.Competing Interest StatementP.F. is beneficiary of a license contract on thin-film electrodes with Blackrock Microsystems LLC (Salt Lake City, UT), member of the Scientific Technical Advisory Board of CorTec GmbH (Freiburg, Germany), and managing director of Brain Science GmbH (Frankfurt am Main, Germany).