RT Journal Article
SR Electronic
T1 Scanning The Horizon: Future challenges for neuroimaging research
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 059188
DO 10.1101/059188
A1 Russell A. Poldrack
A1 Chris I. Baker
A1 Joke Durnez
A1 Krzysztof J. Gorgolewski
A1 Paul M. Matthews
A1 Marcus Munafò
A1 Thomas E. Nichols
A1 Jean-Baptiste Poline
A1 Edward Vul
A1 Tal Yarkoni
YR 2016
UL http://biorxiv.org/content/early/2016/06/16/059188.abstract
AB Neuroimaging has transformed our ability to probe the neurobiological basis of behaviour. As neuroimaging technologies become more widely available, they are increasingly being applied by the wider neuroscience community. However, concerns have recently been raised that the conclusions drawn from many human neuroimaging studies are either spurious or not generalizable. Problems such as low statistical power, analytical flexibility, and lack of direct replication apply to many fields, but perhaps particularly to neuroimaging. In this Opinion article, we discuss these problems, outline current and suggested best practices to improve the quality and reproducibility of neuroimaging findings, and describe how we think the field should evolve if it is to produce the most meaningful answers to current and future research questions.