PT  - JOURNAL ARTICLE
AU  - M. Mirdita
AU  - M. Steinegger
AU  - F. Breitwieser
AU  - J. Söding
AU  - E. Levy Karin
TI  - Fast and sensitive taxonomic assignment to metagenomic contigs
AID  - 10.1101/2020.11.27.401018
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.11.27.401018
4099  - http://biorxiv.org/content/early/2020/11/27/2020.11.27.401018.short
4100  - http://biorxiv.org/content/early/2020/11/27/2020.11.27.401018.full
AB  - MMseqs2 taxonomy is a new tool to assign taxonomic labels to metagenomic contigs. It extracts all possible protein fragments from each contig, quickly retains those that can contribute to taxonomic annotation, assigns them with robust labels and determines the contig’s taxonomic identity by weighted voting. Its fragment extraction step is suitable for the analysis of all domains of life. MMseqs2 taxonomy is 2-18x faster than state-of-the-art tools and also contains new modules for creating and manipulating taxonomic reference databases as well as reporting and visualizing taxonomic assignments.Availability MMseqs2 taxonomy is part of the MMseqs2 free open-source software package available for Linux, macOS and Windows at https://mmseqs.com.Competing Interest StatementThe authors have declared no competing interest.