RT Journal Article
SR Electronic
T1 Variation in pyrethroid resistance phenotypes in <em>Anopheles darlingi</em> from residual malaria transmission area: warning on suspected resistance built-up in French Guiana
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.12.21.423491
DO 10.1101/2020.12.21.423491
A1 Samuel Vezenegho
A1 Romuald Carinci
A1 Jean Issaly
A1 Christophe Nguyen
A1 Pascal Gaborit
A1 Laetitia Ferraro
A1 Guillaume Lacour
A1 Emilie Mosnier
A1 Vincent Pommier de Santi
A1 Yanouk Epelboin
A1 Romain Girod
A1 Sébastien Briolant
A1 Isabelle Dusfour
YR 2020
UL http://biorxiv.org/content/early/2020/12/21/2020.12.21.423491.abstract
AB Anopheles darlingi is the major vector of malaria in South America. In French Guiana, malaria transmission occurs inland and along the rivers with a particular reemergence in the lower Oyapock area. Control against malaria vector is performed using deltamethrin indoor residual spraying and long lasting impregnated bednets. For four years, the level of resistance to pyrethroids was monitored using CDC bottle tests in An. darlingi populations. Resistance built-up was suspected in a mosquito population in malaria endemic area but did not sustained, supposably due to the reintroduction of susceptible alleles. No mutation on the insecticide target genes was found, metabolic resistance is then suspected.Competing Interest StatementThe authors have declared no competing interest.