RT Journal Article
SR Electronic
T1 GeneFriends 2021: Updated co-expression databases and tools for human and mouse genes and transcripts
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.01.10.426125
DO 10.1101/2021.01.10.426125
A1 Priyanka Raina
A1 Inês Lopes
A1 Kasit Chatsirisupachai
A1 Zoya Farooq
A1 João Pedro de Magalhães
YR 2021
UL http://biorxiv.org/content/early/2021/01/10/2021.01.10.426125.abstract
AB Gene co-expression analysis has emerged as a powerful method to provide insights into gene function and regulation. The rapid growth of publicly available RNA-sequencing (RNA-seq) data has created opportunities for researchers to employ this abundant data to help decipher the complexity and biology of genomes. Co-expression networks have proven effective for inferring relationship between the genes, for gene prioritization and for assigning function to poorly annotated genes based on their co-expressed partners. To facilitate such analyses we created previously an online co-expression tool for humans and mice entitled GeneFriends. To continue providing a valuable tool to the scientific community, we have updated the GeneFriends database. Here, we present the latest version of GeneFriends, which includes updated gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples. GeneFriends is freely available at http://www.genefriends.org/Competing Interest StatementThe authors have declared no competing interest.