RT Journal Article
SR Electronic
T1 Cepo uncovers cell identity through differential stability
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.01.10.426138
DO 10.1101/2021.01.10.426138
A1 Hani Jieun Kim
A1 Kevin Wang
A1 Carissa Chen
A1 Yingxin Lin
A1 Patrick PL Tam
A1 David M Lin
A1 Jean YH Yang
A1 Pengyi Yang
YR 2021
UL http://biorxiv.org/content/early/2021/01/11/2021.01.10.426138.abstract
AB We present Cepo, a method to generate cell-type-specific gene statistics of differentially stable genes from single-cell RNA-sequencing (scRNA-seq) data to define cell identity. Cepo outperforms current methods in assigning cell identity and enhances several cell identification applications such as cell-type characterisation, spatial mapping of single cells, and lineage inference of single cells.Competing Interest StatementThe authors have declared no competing interest.