RT Journal Article
SR Electronic
T1 Transcranial direct current stimulation does not improve performance in a whole-body movement task
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.01.25.428100
DO 10.1101/2021.01.25.428100
A1 Harriet Caesley
A1 Isabella Sewell
A1 Nikita Gogineni
A1 Amir-Homayoun Javadi
YR 2021
UL http://biorxiv.org/content/early/2021/01/26/2021.01.25.428100.abstract
AB Research has investigated the use of non-invasive brain interventions, such as transcranial direct current stimulation (tDCS), to enhance motor learning and rehabilitation. Much research has shown that tDCS improves motor learning and that bilateral tDCS is more beneficial than unilateral tDCS in improving motor learning. However, past research has primarily utilised simple motor tasks in measuring motor skill learning. These are not ecologically reliable as whole-body movement is required for everyday activities. This study involved two experiments. Each experiment involved participants learning 12 Ballroom and Latin dance moves whilst undergoing tDCS. All participants underwent three sessions of tDCS, (unilateral, bilateral and sham), over three consecutive days. Participants in the first experiment (n=30) had stimulation to the primary motor cortex (PMC) and those in the second experiment (n=31) had stimulation to the dorsolateral prefrontal cortex (DLPFC). In each experiment, a baseline was taken before the training sessions and two outcome measures were taken; a day after the last training session and two weeks later. In each testing session participants’ dance ability was measured. Our results showed that bilateral tDCS impaired performance in both experiments. Unilateral stimulation impaired performance in the first experiment, and did not significantly improve performance any better than the sham stimulation in the second experiment. These results suggest that task complexity plays a crucial role when tDCS procedures are used to modulate motor performance and highlights possible limitations of tDCS in practice.Competing Interest StatementThe authors have declared no competing interest.