RT Journal Article
SR Electronic
T1 Functional Cliques in Developmentally Correlated Neural Networks
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 064147
DO 10.1101/064147
A1 Luccioli, S.
A1 Barzilai, A.
A1 Ben-Jacob, E.
A1 Bonifazi, P.
A1 Torcini, A.
YR 2016
UL http://biorxiv.org/content/early/2016/07/18/064147.abstract
AB We consider a sparse random network of excitatory leaky integrate-andfire neurons with short-term synaptic depression. Furthermore to mimic the dynamics of a brain circuit in its first stages of development we introduce for each neuron correlations among in-degree and out-degree as well as among excitability and the corresponding total degree, We analyze the influence of single neuron stimulation and deletion on the collective dynamics of the network. We show the existence of a small group of neurons capable of controlling and even silencing the bursting activity of the network. These neurons form a functional clique since only their activation in a precise order and within specific time windows is capable to ignite population bursts.