%0 Journal Article %A Daniel García Murillo %A Ora Rogovin %A Yixin Zhao %A Shufei Chen %A Ziqi Wang %A Zoey C. Keeley %A Daniel I. Shin %A Victor M. Suárez Casanova %A Yannan Zhu %A Lisandro Martin %A Olga Papaemmanouil %A Stephen D. Van Hooser %T NDI: A platform-independent data interface and database for neuroscience physiology and imaging experiments %D 2021 %R 10.1101/2020.05.13.093542 %J bioRxiv %P 2020.05.13.093542 %X Collaboration in neuroscience is impeded by the difficulty of sharing primary data, results, and software across labs. Here we introduce Neuroscience Data Interface (NDI), a platform-independent standard that allows an analyst to use and create software that functions independently from the format of the raw data or the manner in which the data is organized into files. The interface is rooted in a simple vocabulary that describes common apparatus and storage devices used in neuroscience experiments. Results of analyses – and analyses of analyses – are stored as documents in a scalable, queryable database that stores the relationships and history among the experiment elements and documents. The interface allows the development of an application ecosystem where applications can focus on calculation rather than data format or organization. This tool can be used by individual labs to exchange and analyze data, and it can serve to curate neuroscience data for searchable archives.Competing Interest StatementThe authors have declared no competing interest. %U https://www.biorxiv.org/content/biorxiv/early/2021/02/16/2020.05.13.093542.full.pdf