RT Journal Article
SR Electronic
T1 TP-MAP - an Integrated Software Package for the Analysis of 1D and 2D Thermal Profiling Data
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.02.22.432361
DO 10.1101/2021.02.22.432361
A1 Felix Feyertag
A1 Kilian V.M. Huber
YR 2021
UL http://biorxiv.org/content/early/2021/02/24/2021.02.22.432361.abstract
AB Thermal profiling (TP) has emerged as a promising experimental methodology for elucidating the molecular targets of drugs and metabolites on a proteome-wide scale. Here, we present the Thermal Profiling Meltome Analysis Program (TP-MAP) software package for the analysis and ranking of 1D and 2D thermal profiling datasets. TP-MAP provides a user-friendly interface to quickly identify hit candidates and further explore targets of interest via intersection and crosslinking to public databases.Competing Interest StatementThe authors have declared no competing interest.