PT - JOURNAL ARTICLE AU - Samantha S. Cohen AU - Christopher Baldassano TI - Developmental changes in story-evoked responses in the neocortex and hippocampus AID - 10.1101/2021.04.12.439526 DP - 2021 Jan 01 TA - bioRxiv PG - 2021.04.12.439526 4099 - http://biorxiv.org/content/early/2021/04/12/2021.04.12.439526.short 4100 - http://biorxiv.org/content/early/2021/04/12/2021.04.12.439526.full AB - Child development, Inter-subject correlation, event segmentation, fMRI, perception, hippocampus, Hidden Markov Model, NarrativeHighlights- Brain responses to a narrative movie change throughout the neocortex and hippocampus during development- Event representations largely become more stable and occur earlier in time with age- Hippocampal responses to event boundaries decrease during childhoodSummary How does the representation of naturalistic life events change with age? Here we analyzed fMRI data from 415 children and adolescents (5 - 19 years) as they watched a narrative movie. In addition to changes in the degree of inter-subject correlation (ISC) with age in sensory and medial parietal regions, we used a novel measure (between-groups ISC) to reveal age-related shifts in the responses across the majority of the neocortex. Over the course of development, brain responses became more discretized into stable and coherent events, and shifted earlier in time to anticipate upcoming event transitions. However, hippocampal responses to event boundaries actually decreased with age, suggesting a shifting division of labor between episodic encoding processes and schematic event representations between the ages of 5 and 19.Competing Interest StatementThe authors have declared no competing interest.