TY - JOUR T1 - GeneCodis 4: Expanding the modular enrichment analysis to regulatory elements JF - bioRxiv DO - 10.1101/2021.04.15.439962 SP - 2021.04.15.439962 AU - A. García-Moreno AU - R. López-Domínguez AU - A. Ramirez-Mena AU - A. Pascual-Montano AU - E. Aparicio-Puerta AU - M. Hackenberg AU - P. Carmona-Saez Y1 - 2021/01/01 UR - http://biorxiv.org/content/early/2021/04/15/2021.04.15.439962.abstract N2 - GeneCodis is a web-based tool for functional enrichment analysis that allows researchers to integrate different sources of annotations. It extracts sets of significant concurrent annotations and assigns a statistical score to evaluate those that are significantly enriched in the input list. Since its first release in 2007, it has been widely employed to analyze lists of genes in order to interpret the underlying biological mechanisms. Here we present GeneCodis 4, a new release that expands the functional analysis provided by the application, to accept regulatory elements, including lists of, transcription factors, CpG sites and miRNAs. It also incorporates new annotation databases and improved interactive visualizations functionalities to explore results. GeneCodis 4 is freely available at https://genecodis.genyo.es.Competing Interest StatementThe authors have declared no competing interest. ER -