RT Journal Article
SR Electronic
T1 GeneCodis 4: Expanding the modular enrichment analysis to regulatory elements
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.04.15.439962
DO 10.1101/2021.04.15.439962
A1 A. García-Moreno
A1 R. López-Domínguez
A1 A. Ramirez-Mena
A1 A. Pascual-Montano
A1 E. Aparicio-Puerta
A1 M. Hackenberg
A1 P. Carmona-Saez
YR 2021
UL http://biorxiv.org/content/early/2021/04/15/2021.04.15.439962.abstract
AB GeneCodis is a web-based tool for functional enrichment analysis that allows researchers to integrate different sources of annotations. It extracts sets of significant concurrent annotations and assigns a statistical score to evaluate those that are significantly enriched in the input list. Since its first release in 2007, it has been widely employed to analyze lists of genes in order to interpret the underlying biological mechanisms. Here we present GeneCodis 4, a new release that expands the functional analysis provided by the application, to accept regulatory elements, including lists of, transcription factors, CpG sites and miRNAs. It also incorporates new annotation databases and improved interactive visualizations functionalities to explore results. GeneCodis 4 is freely available at https://genecodis.genyo.es.Competing Interest StatementThe authors have declared no competing interest.