RT Journal Article
SR Electronic
T1 Tracking the emergence of location-based spatial representations
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 547976
DO 10.1101/547976
A1 Sam C. Berens
A1 Bárður H. Joensen
A1 Aidan J. Horner
YR 2019
UL http://biorxiv.org/content/early/2019/02/26/547976.abstract
AB Scene-selective regions of the human brain form allocentric representations of locations in our environment. These representations are independent of heading direction and allow us to know where we are regardless of our direction of travel. However, we know little about how these location-based representations are formed. Using fMRI representational similarity analysis, we tracked the emergence of location-based representations in scene-selective brain regions. We estimated patterns of activity for two distinct scenes, taken before and after participants learnt they were from the same location. During a learning phase, we presented participants with two types of panoramic videos: (1) an overlap video condition displaying two distinct scenes (0° and 180°) from the same location, and (2) a no-overlap video displaying two distinct scenes from different locations (that served as a control condition). In the parahippocampal cortex (PHC) and retrosplenial cortex (RSC), representations of scenes from the same location became more similar to each other only after they had been shown in the overlap condition, suggesting the emergence of location-based viewpoint-independent representations. Whereas location-based representations emerged in the PHC regardless of subsequent behaviour, RSC representations only emerged for locations where participants could behaviourally identify the two scenes as belonging to the same location. The results demonstrate that we can track the emergence of location-based representations in the PHC and RSC in a single fMRI session and suggest that the RSC plays a key role in using such representations to locate ourselves in space.