RT Journal Article
SR Electronic
T1 Genomic Abelian Finite Groups
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.06.01.446543
DO 10.1101/2021.06.01.446543
A1 Robersy Sanchez
A1 Jesús Barreto
YR 2021
UL http://biorxiv.org/content/early/2021/06/02/2021.06.01.446543.abstract
AB Experimental studies reveal that genome architecture splits into natural domains suggesting a well-structured genomic architecture, where, for each species, genome populations are integrated by individual mutational variants. Herein, we show that the architecture of population genomes from the same or closed related species can be quantitatively represented in terms of the direct sum of homocyclic abelian groups defined on the genetic code, where populations from the same species lead to the same canonical decomposition into p-groups. This finding unveils a new ground for the application of the abelian group theory to genomics and epigenomics, opening new horizons for the study of the biological processes (at genomic scale) and provides new lens for genomic medicine.Competing Interest StatementThe authors have declared no competing interest.