RT Journal Article
SR Electronic
T1 The influence of stimulus and behavioral histories on predictive control of smooth pursuit eye movements
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.06.05.447182
DO 10.1101/2021.06.05.447182
A1 Takeshi Miyamoto
A1 Yutaka Hirata
A1 Akira Katoh
A1 Kenichiro Miura
A1 Seiji Ono
YR 2021
UL http://biorxiv.org/content/early/2021/06/07/2021.06.05.447182.abstract
AB The pursuit system has the ability to perform predictive control of eye movements. Even when the target motion is unpredictable due to velocity or direction changes, preceding changes in eye velocity are generated based on weighted averaging of past stimulus timing. However, it is still uncertain whether behavioral history influences the control of predictive pursuit. Thus, we attempted to clarify the influences of stimulus and behavioral histories on predictive pursuit to randomized target velocity. We used alternating-ramp stimuli, where the rightward velocity was fixed while the leftward velocity was either fixed (predictable) or randomized (unpredictable). Predictive eye deceleration was observed regardless of whether the target velocity was predictable or not. In particular, the predictable condition showed that the predictive pursuit responses corresponded to future target velocity. The linear mixed-effects model showed that both stimulus and behavioral histories of the previous two or three trials had influences on the predictive pursuit responses to the unpredictable target velocity. Our results suggest that the predictive pursuit system allows to track randomized target motion using the information from previous several trials, and the information of sensory input (stimulus) and motor output (behavior) in the past time sequences have partially different influences on predictive pursuit.Competing Interest StatementThe authors have declared no competing interest.