RT Journal Article SR Electronic T1 MicroMator: Open and Flexible Software for Reactive Microscopy JF bioRxiv FD Cold Spring Harbor Laboratory SP 2021.03.12.435206 DO 10.1101/2021.03.12.435206 A1 Zachary R Fox A1 Steven Fletcher A1 Achille Fraisse A1 Chetan Aditya A1 Sebastián Sosa-Carrillo A1 Sébastien Gilles A1 François Bertaux A1 Jakob Ruess A1 Gregory Batt YR 2021 UL http://biorxiv.org/content/early/2021/06/10/2021.03.12.435206.abstract AB Microscopy image analysis has recently made enormous progress both in terms of accuracy and speed thanks to machine learning methods. This greatly facilitates the online adaptation of microscopy experimental plans using real-time information of the observed systems and their environments. Here we report MicroMator, an open and flexible software for defining and driving reactive microscopy experiments, and present applications to single-cell control and single-cell recombination.Competing Interest StatementThe authors have declared no competing interest.