PT  - JOURNAL ARTICLE
AU  - Philippe Chlenski
AU  - Melody Hsu
AU  - Itsik Pe’er
TI  - MiSDEED: a synthetic multi-omics engine for microbiome power analysis and study design
AID  - 10.1101/2021.08.09.455682
DP  - 2021 Jan 01
TA  - bioRxiv
PG  - 2021.08.09.455682
4099  - http://biorxiv.org/content/early/2021/08/10/2021.08.09.455682.short
4100  - http://biorxiv.org/content/early/2021/08/10/2021.08.09.455682.full
AB  - Summary MiSDEED is a command-line tool for generating synthetic longitudinal multi-omics data from simulated microbial environments. It generates relative-abundance timecourses under perturbations for an arbitrary number of samples and patients. All simulation parameters are exposed to the user to facilitate rapid power analysis and aid in study design. Users who want additional flexibility may also use MiSDEED as a Python package.Availability and implementation MiSDEED is written in Python and is freely available at https://github.com/pchlenski/misdeed.Contact pac{at}cs.columbia.eduCompeting Interest StatementThe authors have declared no competing interest.