TY - JOUR T1 - dbOTU3: A new implementation of distribution-based OTU calling JF - bioRxiv DO - 10.1101/076927 SP - 076927 AU - Scott Olesen AU - Claire Duvallet AU - Eric Alm Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/09/22/076927.abstract N2 - Distribution-based operational taxonomic unit-calling (dbOTU) improves on other approaches by incorporating information about the input sequences’ distribution across samples. Previous implementations of dbOTU presented challenges for users. Here we introduce and evaluate a new implementation of dbOTU that is faster and more user-friendly. We show that this new implementation has theoretical and practical improvements over previous implementations of dbOTU, making the algorithm more accessible to microbial ecology and biomedical researchers. ER -