RT Journal Article
SR Electronic
T1 The ribbon architecture of the Golgi apparatus is not restricted to vertebrates
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.09.10.459720
DO 10.1101/2021.09.10.459720
A1 Giovanna Benvenuto
A1 Maria Ina Arnone
A1 Francesco Ferraro
YR 2021
UL http://biorxiv.org/content/early/2021/09/10/2021.09.10.459720.abstract
AB The Golgi apparatus plays a central role as a processing and sorting station along the secretory pathway. In multicellular organisms, this organelle displays two structural organizations, whereby its functional subunits, the mini-stacks, are either dispersed throughout the cell or linked into a centralized structure, called Golgi “ribbon”. The Golgi ribbon is considered to be a feature typical of vertebrate cells. Here we report that this is not the case. We show that sea urchin embryonic cells assemble Golgi ribbons during early development. Sea urchins are deuterostomes, the bilaterian animal clade to which chordates, and thus vertebrates, also belong.Far from being a structural innovation of vertebrates, the Golgi ribbon therefore appears to be an ancient cellular feature evolved before the split between echinoderms and chordates. Evolutionary conservation of the ribbon architecture surmises that it must play fundamental roles in the biology of deuterostomes.Competing Interest StatementThe authors have declared no competing interest.