PT - JOURNAL ARTICLE AU - Wang, Lingyan AU - Yau, Jeffrey M. TI - Signatures of vibration frequency tuning in human neocortex AID - 10.1101/2021.10.03.462923 DP - 2021 Jan 01 TA - bioRxiv PG - 2021.10.03.462923 4099 - http://biorxiv.org/content/early/2021/10/04/2021.10.03.462923.short 4100 - http://biorxiv.org/content/early/2021/10/04/2021.10.03.462923.full AB - Humans can perceive and discriminate vibration frequency, yet the central representation of this fundamental feature is unknown. Using fMRI, we discovered that cortical responses are tuned for vibration frequency. Voxel tuning was biased in a manner that reflects perceptual sensitivity and the response profile of the Pacinian afferent system. These results imply the existence of tuned populations that may encode naturalistic vibrations according to their constituent spectra.Competing Interest StatementThe authors have declared no competing interest.