TY - JOUR T1 - Automated Optimization of Residual Reduction Algorithm Parameters in OpenSim JF - bioRxiv DO - 10.1101/2021.10.06.463431 SP - 2021.10.06.463431 AU - Jordan T. Sturdy AU - Anne K. Silverman AU - Nathan T. Pickle Y1 - 2021/01/01 UR - http://biorxiv.org/content/early/2021/10/08/2021.10.06.463431.abstract N2 - The residual reduction algorithm (RRA) in OpenSim improves dynamic consistency of movement simulations of musculoskeletal models. RRA requires the user to select numerous tracking weights for the joint kinematics to reduce residual errors. Selection is often performed manually, which can be time-consuming and is unlikely to yield optimal tracking weights. A multi-heuristic optimization algorithm was employed to expedite tracking weight decision making to reduce residual errors. This method produced more rigorous results than manual iterations and although the total computation time was not significantly reduced, this method does not require the user to monitor the algorithm’s progress to find a solution, thereby reducing manual tuning. Supporting documentation and code to implement this optimization is freely provided to assist the community with developing movement simulations.Competing Interest StatementThe authors have declared no competing interest. ER -