RT Journal Article
SR Electronic
T1 COBREXA.jl: constraint-based reconstruction and exascale analysis
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.06.04.447038
DO 10.1101/2021.06.04.447038
A1 Miroslav Kratochvíl
A1 Laurent Heirendt
A1 St. Elmo Wilken
A1 Taneli Pusa
A1 Sylvain Arreckx
A1 Alberto Noronha
A1 Marvin van Aalst
A1 Venkata P Satagopam
A1 Oliver Ebenhöh
A1 Reinhard Schneider
A1 Christophe Trefois
A1 Wei Gu
YR 2021
UL http://biorxiv.org/content/early/2021/10/10/2021.06.04.447038.abstract
AB COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate how the design promotes analysis scalability on several use-cases with multi-organism community models.Availability and implementation https://doi.org/10.17881/ZKCR-BT30.Contact christophe.trefois{at}uni.lu, wei.gu{at}uni.luCompeting Interest StatementThe authors have declared no competing interest.