RT Journal Article
SR Electronic
T1 The PRO model accounts for the anterior cingulate cortex role in risky decision-making and monitoring
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.10.13.464327
DO 10.1101/2021.10.13.464327
A1 Jae Hyung Woo
A1 Habiba Azab
A1 Andrew Jahn
A1 Benjamin Hayden
A1 Joshua W. Brown
YR 2021
UL http://biorxiv.org/content/early/2021/10/15/2021.10.13.464327.abstract
AB The anterior cingulate cortex (ACC) has been implicated in a number of functions including performance monitoring and decision making involving effort. The prediction of responses and outcomes (PRO) model has provided a unified account of much human and monkey ACC data involving anatomy, neurophysiology, EEG, fMRI, and behavior. Here we explore the computational nature of ACC with the PRO model, extending it to account specifically for both human and macaque monkey decision-making under risk, including both behavioral and neural data. We show that the PRO model can account for a number of additional effects related to outcome prediction, decision-making under risk, gambling behavior, and we show that the ACC represents the variance of uncertain outcomes, suggesting a link between ACC function and mean-variance theories of decision making. The PRO model provides a unified account of a large set of data regarding the ACC.Competing Interest StatementThe authors have declared no competing interest.