PT - JOURNAL ARTICLE AU - Jesse J. Kwiek AU - Christopher R. Pickett AU - Chloe A. Flanigan AU - Marcia V. Lee AU - Linda J. Saif AU - Jeff Jahnes AU - Greg Blonder TI - A practical PPE decontamination method using warm air and ambient humidity AID - 10.1101/2020.11.12.380196 DP - 2021 Jan 01 TA - bioRxiv PG - 2020.11.12.380196 4099 - http://biorxiv.org/content/early/2021/10/15/2020.11.12.380196.short 4100 - http://biorxiv.org/content/early/2021/10/15/2020.11.12.380196.full AB - Despite a year-and-a-half of Sars-CoV-2 pandemic experience, personal protective equipment (PPE) remains in short supply1. Current decontamination methods are complex, slow, expensive and particularly ill-suited for low to middle income nations where the need is greatest. We propose a low temperature, ambient humidity decontamination method (WASP-D) based on the thirty minute or less half-life of Sars-CoV-2 (and other common pathogens) at temperatures above 45°C, combined with the observation that most PPE are designed to be safely transported and stored at temperatures below 50°C. Decontamination at 12 hours, 46°C (115°F) and ambient humidity should consistently reduce SARS-CoV-2 viral load by a factor of 106, without negatively affecting PPE materials or performance.Competing Interest StatementThe authors have declared no competing interest.