TY - JOUR T1 - A Landmark-based Common Coordinate Framework for Spatial Transcriptomics Data JF - bioRxiv DO - 10.1101/2021.11.11.468178 SP - 2021.11.11.468178 AU - Alma Andersson AU - Žaneta Andrusivová AU - Paulo Czarnewski AU - Xiaofei Li AU - Erik Sundström AU - Joakim Lundeberg Y1 - 2021/01/01 UR - http://biorxiv.org/content/early/2021/11/13/2021.11.11.468178.abstract N2 - The increasing amount of spatial transcriptomics data prompts for means to amalgamate observations from distinct experiments, especially attractive is to cast quantities from different sources into a common coordinate frame-work (CCF) to relate signals across space. We here present a method that enables transfer of information from multiple samples to a reference representing a CCF, and show its utility by analyzing an assortment of real and synthetic data sets.Competing Interest StatementA.A., Z.A. and J.L. are scientific advisors for 10x Genomics Inc., providing spatially barcoded slides. The remaining authors declare no competing interests. ER -