RT Journal Article
SR Electronic
T1 Local adaptation mediated niche expansion in correlation with genetic richness
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.11.22.469607
DO 10.1101/2021.11.22.469607
A1 Masaomi Kurokawa
A1 Issei Nishimura
A1 Bei-Wen Ying
YR 2021
UL http://biorxiv.org/content/early/2021/11/22/2021.11.22.469607.abstract
AB As a central issue in evolution and ecology, the quantitative relationship among the genome, adaptation and the niche was investigated. Local adaptation of five Escherichia coli strains carrying either the wild-type genome or reduced genomes was achieved by experimental evolution. A high-throughput fitness assay of the ancestor and evolved populations across an environmental gradient of eight niches resulted in a total of 80 fitness curves generated from 2,220 growth curves. Further analyses showed that the increases in both local adaptiveness and niche broadness were negatively correlated with genetic richness. Local adaptation caused common niche expansion, whereas niche expansion for generality or speciality was decided by genetic richness. The order of the mutations accumulated stepwise was correlated with the magnitude of the fitness increase attributed to mutation accumulation. Pre-adaptation probably participated in coordination among genetic richness, local adaptation and niche expansion.Competing Interest StatementThe authors have declared no competing interest.