RT Journal Article
SR Electronic
T1 Ribbon: Visualizing complex genome alignments and structural variation
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 082123
DO 10.1101/082123
A1 Maria Nattestad
A1 Chen-Shan Chin
A1 Michael C. Schatz
YR 2016
UL http://biorxiv.org/content/early/2016/10/20/082123.abstract
AB To the Editor Visualization has played an extremely important role in the current genomic revolution to inspect and understand variants, expression patterns, evolutionary changes, and a number of other relationships1–3. However, most of the information in read-to-reference or genome-genome alignments is lost for structural variations in the one-dimensional views of most genome browsers showing only reference coordinates. Instead, structural variations captured by long reads or assembled contigs often need more context to understand, including alignments and other genomic information from multiple chromosomes.