RT Journal Article
SR Electronic
T1 Temporal-sensitive prefrontal involvement in associating confidence with task performance illustrates metacognitive introspection in Old World monkeys (<em>Macaca mulatta</em>)
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.11.30.470665
DO 10.1101/2021.11.30.470665
A1 Yudian Cai
A1 Zhiyong Jin
A1 Chenxi Zhai
A1 Huimin Wang
A1 Jijun Wang
A1 Yingying Tang
A1 Sze Chai Kwok
YR 2021
UL http://biorxiv.org/content/early/2021/12/02/2021.11.30.470665.abstract
AB Metacognition refers to the ability to be aware of one’s own cognition. Ample evidence indicate that metacognition in the human primate is highly dissociable from cognition, specialized across domains, and subserved by distinct neural substrates. However, these aspects remain relatively understudied in the macaque monkeys. Here we investigated the functionality of macaques’ metacognition by combining a confidence proxy, hierarchical Bayesian meta-d’ computational modelling, and single-pulse transcranial magnetic stimulation technique. We found a critical role of Brodmann Area 46d (BA 46d) in supporting metacognition without implicating task performance and its critical time-sensitive role in meta-calculation. We additionally revealed that macaque metacognition is highly domain-specific with respect to memory and perception decisions. These findings carry implications for our understanding of metacognitive introspection within the primate lineage.Competing Interest StatementThe authors have declared no competing interest.