TY - JOUR T1 - The <em>Streptococcus agalactiae</em> R3 surface protein is encoded by <em>sar5</em> JF - bioRxiv DO - 10.1101/2022.01.17.476664 SP - 2022.01.17.476664 AU - Marte Singsås Dragset AU - Adelle Basson AU - Camilla Olaisen AU - Linn-Karina Selvik AU - Randi Valsø Lyng AU - Hilde Lysvand AU - Christina Gabrielsen Aas AU - Jan Egil Afset Y1 - 2022/01/01 UR - http://biorxiv.org/content/early/2022/01/17/2022.01.17.476664.abstract N2 - Streptococcus agalactiae (a group B streptococcus; GBS) is an important human pathogen causing pneumonia, sepsis and meningitis in neonates, as well as infections in pregnant women, immunocompromised individuals, and the elderly. For the future control of GBS-inflicted disease, GBS surface exposed proteins are particularly relevant as they may act as antigens for vaccine development and/or as serosubtype markers in epidemiological settings. Even so, the genes encoding some of the surface proteins established as serosubtype markers by antibody-based methods are still unknown. Here, we identify sar5 as the gene encoding the R3 surface protein, a serosubtype marker of hitherto unknown genetic origin.Competing Interest StatementThe authors have declared no competing interest. ER -