PT - JOURNAL ARTICLE AU - Lucas, Anastasia AU - Verma, Anurag AU - Ritchie, Marylyn D. TI - hudson: A User-Friendly R Package to Extend Manhattan Plots AID - 10.1101/2022.01.25.474274 DP - 2022 Jan 01 TA - bioRxiv PG - 2022.01.25.474274 4099 - http://biorxiv.org/content/early/2022/01/27/2022.01.25.474274.short 4100 - http://biorxiv.org/content/early/2022/01/27/2022.01.25.474274.full AB - The Manhattan plot is one of the most widely used visualization techniques when plotting summary statistics from genome-wide or phenome-wide association studies. While there are a number of existing tools to create these plots, there is room for extending their utility to satisfy increasingly complex and comprehensive analyses as well as the need for comparisons between different sets of results or between discovery and replication datasets. The R package presented here, hudson, provides user-friendly plotting functions intended for use with genome, phenome, and exposome-wide association studies, but its flexible framework can be utilized for a wide variety genome-wide analyses. Further, we have extended these figures to allow for interactive elements to facilitate results exploration for the ever-increasing large-scale dimensionality of these data. hudson can be obtained from https://github.com/RitchieLab/hudson.Competing Interest StatementThe authors have declared no competing interest.