RT Journal Article
SR Electronic
T1 3D Printable High Performance Conducting Polymer Hydrogel for All-Hydrogel Bioelectronics
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2022.01.29.478311
DO 10.1101/2022.01.29.478311
A1 Tao Zhou
A1 Hyunwoo Yuk
A1 Faqi Hu
A1 Jingjing Wu
A1 Fajuan Tian
A1 Heejung Roh
A1 Zequn Shen
A1 Guoying Gu
A1 Jingkun Xu
A1 Baoyang Lu
A1 Xuanhe Zhao
YR 2022
UL http://biorxiv.org/content/early/2022/01/29/2022.01.29.478311.abstract
AB Owing to the unique combination of electrical conductivity and tissue-like mechanical properties, conducting polymer hydrogels have emerged as a promising candidate for bioelectronic interfacing with biological systems. However, despite the recent advances, the development of hydrogels with both excellent electrical and mechanical properties in physiological environments remains a lingering challenge. Here, we report a bi-continuous conducting polymer hydrogel (BC-CPH) that simultaneously achieves high electrical conductivity (over 11 S cm-1), stretchability (over 400%) and fracture toughness (over 3,300 J m-2) in physiological environments, and is readily applicable to advanced fabrication methods including 3D printing. Enabled by the BC-CPH, we further demonstrate multi-material 3D printing of monolithic all-hydrogel bioelectronic interfaces for long-term electrophysiological recording and stimulation of various organs. This study may offer promising materials and a platform for future bioelectronic interfacing.Competing Interest StatementThe authors have declared no competing interest.