RT Journal Article
SR Electronic
T1 Nucleome Browser: An integrative and multimodal data navigation platform for 4D Nucleome
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2022.02.21.481225
DO 10.1101/2022.02.21.481225
A1 Xiaopeng Zhu
A1 Yang Zhang
A1 Yuchuan Wang
A1 Dechao Tian
A1 Andrew S. Belmont
A1 Jason R. Swedlow
A1 Jian Ma
YR 2022
UL http://biorxiv.org/content/early/2022/02/22/2022.02.21.481225.abstract
AB We introduce Nucleome Browser (http://www.nucleome.org), an interactive, multimodal data visualization and exploration platform for 4D Nucleome research. Our tool effectively integrates heterogeneous datasets (e.g., genomics, imaging, 3D genome structure models, and single-cell data) and external data portals by a new adaptive communication mechanism. Nucleome Browser provides a scalable solution for integrating massive amounts of 4D Nucleome data to navigate multiscale nuclear structure and function in a wide range of biological contexts, enabling hypothesis generation and data sharing with the broad community.Competing Interest StatementJ.R.S. is affiliated with Glencoe Software, a commercial company that builds, delivers, supports and integrates image data management systems across academic, biotech and pharmaceutical industries. The remaining authors declare no competing interests.