RT Journal Article
SR Electronic
T1 Majority of choice-related variability in perceptual decisions is present in early sensory cortex
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 207357
DO 10.1101/207357
A1 Morais, Michael J.
A1 Michelson, Charles D.
A1 Chen, Yuzhi
A1 Pillow, Jonathan W.
A1 Seidemann, Eyal
YR 2022
UL http://biorxiv.org/content/early/2022/03/01/207357.abstract
AB While performing challenging perceptual tasks such as detecting a barely visible target, our perceptual reports vary across presentations of identical stimuli. This perceptual variability is presumably caused by neural variability in our brains. How much of the neural variability that correlates with the perceptual variability is present in the primary visual cortex (V1), the first cortical processing stage of visual information? To address this question, we recorded neural population responses from V1 using voltage-sensitive dye imaging while monkeys performed a challenging reaction-time visual detection task. We found that V1 population responses in the period leading to the decision correspond more closely to the monkey’s report than to the visual stimulus. These results, together with a simple computational model that allows one to quantify the captured choice-related variability, suggest that most of this variability is present in V1 as additive noise, and that areas downstream to V1 contain relatively little independent choice-related variability.Competing Interest StatementThe authors have declared no competing interest.