PT - JOURNAL ARTICLE AU - Takanori Kanayama AU - Keita Tanaka AU - Haruna Shimada AU - Koji Ichiyama AU - Sadaharu Higuchi AU - Ikko Kawashima TI - Improving the Safety of Cultured Meat Using Basal Medium Prepared using Food Ingredients AID - 10.1101/2022.03.28.486069 DP - 2022 Jan 01 TA - bioRxiv PG - 2022.03.28.486069 4099 - http://biorxiv.org/content/early/2022/03/29/2022.03.28.486069.short 4100 - http://biorxiv.org/content/early/2022/03/29/2022.03.28.486069.full AB - Currently, meat production involves environmental issues and high costs; one solution to address this may be to produce meat via cell culture. Therefore, there is an urgent demand for the development of cell culture methods that replace raw materials with food materials to produce cultured meat as food. In this study, we designed food-grade-Dulbecco’s Modified Eagle’s Medium (FG-DMEM); when the cells cultured in FG-DMEM and regular DMEM were compared, there was no significant difference in cell growth or differentiation. Therefore, FG-DMEM can be used for research and safe production of cultured meat.Competing Interest StatementThe authors have declared no competing interest.