RT Journal Article SR Electronic T1 Genome Report: Chromosome-level draft assemblies of the snow leopard, African leopard, and tiger (Panthera uncia, Panthera pardus pardus, and Panthera tigris) JF bioRxiv FD Cold Spring Harbor Laboratory SP 2022.04.26.489474 DO 10.1101/2022.04.26.489474 A1 Ellie E. Armstrong A1 Michael G. Campana A1 Katherine A. Solari A1 Simon R. Morgan A1 Oliver A. Ryder A1 Vincent N. Naude A1 Gustaf Samelius A1 Koustubh Sharma A1 Elizabeth A. Hadly A1 Dmitri A. Petrov YR 2022 UL http://biorxiv.org/content/early/2022/04/27/2022.04.26.489474.abstract AB The big cats (genus Panthera) represent some of the most popular and charismatic species on the planet. Although some reference genomes are available for this clade, few are at the chromosome level, inhibiting high-resolution genomic studies. Here, we assemble genomes from three members of the genus, the tiger (Panthera tigris), the snow leopard (Panthera uncia), and the African leopard (Panthera pardus pardus), at chromosome or near-chromosome level. We used a combination of short- and long-read technologies, as well as proximity ligation data from Hi-C technology, to achieve high continuity and contiguity for each individual. We hope these genomes will aid in further evolutionary and conservation research of this iconic group of mammals.Competing Interest StatementThe authors have declared no competing interest.