RT Journal Article
SR Electronic
T1 RBPSponge: genome-wide identification of lncRNAs that sponge RBPs
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 566828
DO 10.1101/566828
A1 Saber HafezQorani
A1 Aissa Houdjedj
A1 Mehmet Arici
A1 Abdesselam Said
A1 Hilal Kazan
YR 2019
UL http://biorxiv.org/content/early/2019/03/15/566828.abstract
AB Summary Long noncoding RNAs (lncRNAs) can act as molecular sponges or decoys for an RNA-binding protein (RBP) through their RBP binding sites, thereby modulating the expression of all target genes of the corresponding RBP of interest. Here, we present a web tool named RBPSponge to explore lncRNAs based on their potential to act as a sponge for an RBP of interest. RBPSponge identifies the occurrences of RBP binding sites and CLIP peaks on lncRNAs, and enables users to run statistical analyses to investigate the regulatory network between lncRNAs, RBPs and targets of RBPs.Availability The web server is available at https://www.RBPSponge.comContact hilal.kazan{at}antalya.edu.tr