RT Journal Article
SR Electronic
T1 DNA Fountain enables a robust and efficient storage architecture
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 074237
DO 10.1101/074237
A1 Yaniv Erlich
A1 Dina Zielinski
YR 2016
UL http://biorxiv.org/content/early/2016/12/04/074237.abstract
AB DNA is an attractive medium to store digital information. Here, we report a storage strategy, called DNA Fountain, that is highly robust and approaches the information capacity per nucleotide. Using our approach, we stored a full computer operating system, movie, and other files with a total of 2.14 × 106 bytes in DNA oligos and perfectly retrieved the information from a sequencing coverage equivalent of a single tile of Illumina sequencing. We also tested a process that can allow 2.18 × 1015 retrievals using the original DNA sample and were able to perfectly decode the data. Finally, we explored the limit of our architecture in terms of bytes per molecules and obtained a perfect retrieval from a density of 215Petabyte/gram of DNA, orders of magnitudes higher than previous techniques.