RT Journal Article
SR Electronic
T1 scatterHatch: an R/Bioconductor package for generating colorblind-friendly scatter plots for single-cell data
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2021.10.07.463279
DO 10.1101/2021.10.07.463279
A1 Guha, Tejas
A1 Fertig, Elana
A1 Deshpande, Atul
YR 2022
UL http://biorxiv.org/content/early/2022/07/22/2021.10.07.463279.abstract
AB Reduced-dimension or spatial in situ scatter plots are widely employed in bioinformatics papers analyzing single-cell data to present phenomena or cell-conditions of interest in cell groups. When displaying these cell groups, color is frequently the only graphical cue used to differentiate them. However, as the complexity of the information presented in these visualizations increases, the usefulness of color as the only visual cue declines, especially for the sizable readership with color-vision deficiencies (CVDs). In this paper, we present scatterHatch, an R package that creates easily interpretable scatter plots by redundant coding of cell groups using colors as well as patterns. We give examples to demonstrate how the scatterHatch plots are more accessible than simple scatter plots when simulated for various types of CVDs.Competing Interest StatementThe authors have declared no competing interest.