RT Journal Article
SR Electronic
T1 Torsion angles to map and visualize the conformational space of a protein
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2022.08.04.502807
DO 10.1101/2022.08.04.502807
A1 Ginn, Helen Mary
YR 2022
UL http://biorxiv.org/content/early/2022/08/05/2022.08.04.502807.abstract
AB Present understanding of protein structure dynamics trails behind that of static structures. Representation of protein entities (RoPE), based on torsion angles, derives an interpretable conformational space which correlates with data collection temperature, resolution and reaction coordinate. This indicates that torsion angles are a more sensitive and biologically relevant descriptor for protein conformation than atomic coordinates.Competing Interest StatementThe authors have declared no competing interest.